The Baseline African Sepsis Incidence Survey (BASIS)

The Baseline African Sepsis Incidence Survey (BASIS) is a study carried out at health facilities within 10 countries in sub-Saharan Africa, to better understand the burden of sepsis in Africa and better characterise case definitions.

The study will initiate a multi-country, short period observational study of sepsis related admissions in African hospitals. The study will:

a) provide an incidence and point-prevalence estimate of community-acquired sepsis in each of the 10 selected countries;

b) collect data to inform evaluation of existing sepsis definitions and

c) describe capability of sites to identify and treat sepsis.

The aims are the study are:

Estimate incidence of sepsis among non-pregnant adults in sub-Saharan Africa utilizing prevalence and catchment area data from Burkina Faso, Cameroon, Democratic Republic of Congo, Ethiopia, Gabon, Ghana, Malawi, Nigeria, Sierra Leone, and Uganda

Assess in-hospital mortality (censored at 2 weeks) and length of hospitalisation among non-pregnant adults with sepsis in sub-Saharan Africa

Describe variation in prevalence and incidence estimates of sepsis in non-pregnant adults within Africa when applying different available sepsis definitions

Assess the resources available and the burden of clinical work in hospitals providing care to patients with sepsis

BASIS will be completed over the course of two 7-day periods approximately six months apart. The 10 partners taking place are:

Malawi – Jamie Rylance

Uganda – Shevin Jacob and Sharon Nyegisa

Burkina Faso – Armel Poda

Cameroon – Bertrand Hugo Mbatchou Nghane

Ethiopia – Dawit Kebede Huluka

DRC – Patrick de Marie Katoto

Gabon - Dr Bayode Romeo Adegbite

Ghana – John Adabie Appiah

Nigeria – Michael Iroezindu

Sierra Leone – Sulaiman Lakoh